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nail art cleaning

hi, im new to nail art and just learning, i seem to make a mess all the time lol what do you use to clean the brushes etc is it just nail varnish remover ?? also can you help, i have 2way nail art pens, can i use them to paint whole nail or do i use ordinary nail polish for the whole nail, and use the 2way just for decoration ?? any tips would be helpful. thanks dianne